Xaira-Therapeutics/X-Cell
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X-Atlas/Pisces
X-Atlas/Pisces is a Perturb-seq atlas containing 25.6 million perturbed single-cell transcriptomes across 16 biologically diverse contexts, including widely used cell lines (HCT116, HEK293T, HepG2), induced pluripotent stem cells (iPSCs), resting and CD3/CD28 activated Jurkat T lymphoma cells, and multi-lineage differentiating iPSCs.
(Coming Soon) The following data will be uploaded to this dataset:
- All cells from X-Atlas/Orion (cells with a valid dual-guide pair from the HCT116 and HEK293T screens)
- Cells containing a valid dual-guide pair AND perturbations in the 200-gene validation set OR a non-targeting control from the HepG2 and iPSC screens
- All cells with a valid dual-guide pair from the Jurkat Resting and Jurkat Active screens
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Models trained or fine-tuned on Xaira-Therapeutics/X-Atlas-Pisces