Daily Papers

Scientific knowledge is a key driver of technological innovation, shaping industrial development and policy decisions worldwide. Understanding how patents incorporate scientific research is essential for assessing the role of academic discoveries in technological progress. Non-Patent References (NPRs) provide a useful indicator of this relationship by revealing the extent to which patents draw upon scientific literature. Here, we show that reliance on scientific research in patents varies significantly across regions. Oceania and Europe display stronger engagement with scientific knowledge, while the Americas exhibit lower reliance. Moreover, NPRs are more likely to be open access than the average scientific publication, a trend that intensifies when Sci-Hub availability is considered. These results highlight the transformative impact of Open Science on global innovation dynamics. By facilitating broader access to research, Open Science strengthens the link between academia and industry, underscoring the need for policies that promote equitable and science-based innovation, particularly in developing regions.

Touch is a crucial sensing modality that provides rich information about object properties and interactions with the physical environment. Humans and robots both benefit from using touch to perceive and interact with the surrounding environment (Johansson and Flanagan, 2009; Li et al., 2020; Calandra et al., 2017). However, no existing systems provide rich, multi-modal digital touch-sensing capabilities through a hemispherical compliant embodiment. Here, we describe several conceptual and technological innovations to improve the digitization of touch. These advances are embodied in an artificial finger-shaped sensor with advanced sensing capabilities. Significantly, this fingertip contains high-resolution sensors (~8.3 million taxels) that respond to omnidirectional touch, capture multi-modal signals, and use on-device artificial intelligence to process the data in real time. Evaluations show that the artificial fingertip can resolve spatial features as small as 7 um, sense normal and shear forces with a resolution of 1.01 mN and 1.27 mN, respectively, perceive vibrations up to 10 kHz, sense heat, and even sense odor. Furthermore, it embeds an on-device AI neural network accelerator that acts as a peripheral nervous system on a robot and mimics the reflex arc found in humans. These results demonstrate the possibility of digitizing touch with superhuman performance. The implications are profound, and we anticipate potential applications in robotics (industrial, medical, agricultural, and consumer-level), virtual reality and telepresence, prosthetics, and e-commerce. Toward digitizing touch at scale, we open-source a modular platform to facilitate future research on the nature of touch.

This work aims to promote Chinese opera research in both musical and speech domains, with a primary focus on overcoming the data limitations. We introduce KunquDB, a relatively large-scale, well-annotated audio-visual dataset comprising 339 speakers and 128 hours of content. Originating from the Kunqu Opera Art Canon (Kunqu yishu dadian), KunquDB is meticulously structured by dialogue lines, providing explicit annotations including character names, speaker names, gender information, vocal manner classifications, and accompanied by preliminary text transcriptions. KunquDB provides a versatile foundation for role-centric acoustic studies and advancements in speech-related research, including Automatic Speaker Verification (ASV). Beyond enriching opera research, this dataset bridges the gap between artistic expression and technological innovation. Pioneering the exploration of ASV in Chinese opera, we construct four test trials considering two distinct vocal manners in opera voices: stage speech (ST) and singing (S). Implementing domain adaptation methods effectively mitigates domain mismatches induced by these vocal manner variations while there is still room for further improvement as a benchmark.

This paper carefully summarizes extensive and profound questions from all walks of life, focusing on the current high-profile AI field, covering multiple dimensions such as industry trends, academic research, technological innovation and business applications. This paper meticulously curates questions that are both thought-provoking and practically relevant, providing nuanced and insightful answers to each. To facilitate readers' understanding and reference, this paper specifically classifies and organizes these questions systematically and meticulously from the five core dimensions of computing power infrastructure, software architecture, data resources, application scenarios, and brain science. This work aims to provide readers with a comprehensive, in-depth and cutting-edge AI knowledge framework to help people from all walks of life grasp the pulse of AI development, stimulate innovative thinking, and promote industrial progress.

Case definitions are essential for effectively communicating public health threats. However, the absence of a standardized, machine-readable format poses significant challenges to interoperability, epidemiological research, the exchange of qualitative data, and the effective application of computational analysis methods, including artificial intelligence (AI). This complicates comparisons and collaborations across organizations and regions, limits data integration, and hinders technological innovation in public health. To address these issues, we propose the first open, machine-readable format for representing case and syndrome definitions. Additionally, we introduce the first comprehensive dataset of standardized case definitions and tools to convert existing human-readable definitions into machine-readable formats. We also provide an accessible online platform for browsing, analyzing, and contributing new definitions, available at https://opensyndrome.org. The Open Syndrome Definition format enables consistent, scalable use of case definitions across systems, unlocking AI's potential to strengthen public health preparedness and response. The source code for the format can be found at https://github.com/OpenSyndrome/schema under the MIT license.

In recent years, with the rapid development of the depth and breadth of large language models' capabilities, various corresponding evaluation benchmarks have been emerging in increasing numbers. As a quantitative assessment tool for model performance, benchmarks are not only a core means to measure model capabilities but also a key element in guiding the direction of model development and promoting technological innovation. We systematically review the current status and development of large language model benchmarks for the first time, categorizing 283 representative benchmarks into three categories: general capabilities, domain-specific, and target-specific. General capability benchmarks cover aspects such as core linguistics, knowledge, and reasoning; domain-specific benchmarks focus on fields like natural sciences, humanities and social sciences, and engineering technology; target-specific benchmarks pay attention to risks, reliability, agents, etc. We point out that current benchmarks have problems such as inflated scores caused by data contamination, unfair evaluation due to cultural and linguistic biases, and lack of evaluation on process credibility and dynamic environments, and provide a referable design paradigm for future benchmark innovation.

This paper examines the fiscal and macroeconomic strategies essential for transition of India to a high income economy by 2047, aligning with the vision of Viksit Bharat. A sustainable annual GDP growth rate of 7 to 8 percent is projected as necessary to achieve this milestone while maintaining fiscal prudence through a targeted deficit threshold below 3.5 percent of GDP. The study underscores the role of disciplined fiscal management in financing critical public investments in infrastructure, human capital development and technological innovation. Given constraints on domestic resource mobilization, the paper highlights the importance of multilateral financial institutions, including the World Bank, IMF and ADB, in expanding fiscal space in India through concessional financing, technical cooperation, and risk sharing mechanisms. Using econometric modeling and scenario analysis, the research identifies key policy interventions in infrastructure, healthcare, education and sustainable energy that can maximize growth while ensuring fiscal sustainability. Policy recommendations include enhancing tax buoyancy, rationalizing expenditure, optimizing public private partnerships and strengthening fiscal responsibility frameworks. The findings suggest that a calibrated approach to growth, prudent fiscal management and strategic international collaborations are critical to achieving long term economic aspirations of India.

Machine learning research, crucial for technological advancements and innovation, often faces significant challenges due to its inherent complexity, slow pace of experimentation, and the necessity for specialized expertise. Motivated by this, we present a new systematic framework, autonomous Machine Learning Research with large language models (MLR-Copilot), designed to enhance machine learning research productivity through the automatic generation and implementation of research ideas using Large Language Model (LLM) agents. The framework consists of three phases: research idea generation, experiment implementation, and implementation execution. First, existing research papers are used to generate hypotheses and experimental plans vis IdeaAgent powered by LLMs. Next, the implementation generation phase translates these plans into executables with ExperimentAgent. This phase leverages retrieved prototype code and optionally retrieves candidate models and data. Finally, the execution phase, also managed by ExperimentAgent, involves running experiments with mechanisms for human feedback and iterative debugging to enhance the likelihood of achieving executable research outcomes. We evaluate our framework on five machine learning research tasks and the experimental results show the framework's potential to facilitate the research progress and innovations.

Large language models (LLMs) have achieved remarkable success across various domains, driving significant technological advancements and innovations. Despite the rapid growth in model scale and capability, systematic, data-driven research on how structural configurations affect performance remains scarce. To address this gap, we present a large-scale dataset encompassing diverse open-source LLM structures and their performance across multiple benchmarks. Leveraging this dataset, we conduct a systematic, data mining-driven analysis to validate and quantify the relationship between structural configurations and performance. Our study begins with a review of the historical development of LLMs and an exploration of potential future trends. We then analyze how various structural choices impact performance across benchmarks and further corroborate our findings using mechanistic interpretability techniques. By providing data-driven insights into LLM optimization, our work aims to guide the targeted development and application of future models. We will release our dataset at https://huggingface.co/datasets/DX0369/LLM-Structure-Performance-Dataset

Climate change poses an urgent global threat, needing the rapid identification and deployment of innovative solutions. We hypothesise that many of these solutions already exist within scientific literature but remain underutilised. To address this gap, this study employs a curated dataset sourced from OpenAlex, a comprehensive repository of scientific papers. Utilising Large Language Models (LLMs), such as GPT4-o from OpenAI, we evaluate title-abstract pairs from scientific papers on seven dimensions, covering climate change mitigation potential, stage of technological development, and readiness for deployment. The outputs of the language models are then compared with human evaluations to assess their effectiveness in identifying promising yet overlooked climate innovations. Our findings suggest that these LLM-based models can effectively augment human expertise, uncovering climate solutions that are potentially impactful but with far greater speed, throughput and consistency. Here, we focused on UK-based solutions, but the workflow is region-agnostic. This work contributes to the discovery of neglected innovations in scientific literature and demonstrates the potential of AI in enhancing climate action strategies.

This paper presents a comprehensive study of Retrieval-Augmented Generation (RAG), tracing its evolution from foundational concepts to the current state of the art. RAG combines retrieval mechanisms with generative language models to enhance the accuracy of outputs, addressing key limitations of LLMs. The study explores the basic architecture of RAG, focusing on how retrieval and generation are integrated to handle knowledge-intensive tasks. A detailed review of the significant technological advancements in RAG is provided, including key innovations in retrieval-augmented language models and applications across various domains such as question-answering, summarization, and knowledge-based tasks. Recent research breakthroughs are discussed, highlighting novel methods for improving retrieval efficiency. Furthermore, the paper examines ongoing challenges such as scalability, bias, and ethical concerns in deployment. Future research directions are proposed, focusing on improving the robustness of RAG models, expanding the scope of application of RAG models, and addressing societal implications. This survey aims to serve as a foundational resource for researchers and practitioners in understanding the potential of RAG and its trajectory in natural language processing.

With the rapid development of large model technology, the application of agent technology in various fields is becoming increasingly widespread, profoundly changing people's work and lifestyles. In complex and dynamic systems, multi-agents achieve complex tasks that are difficult for a single agent to complete through division of labor and collaboration among agents. This paper discusses the integrated application of LangGraph and CrewAI. LangGraph improves the efficiency of information transmission through graph architecture, while CrewAI enhances team collaboration capabilities and system performance through intelligent task allocation and resource management. The main research contents of this paper are: (1) designing the architecture of agents based on LangGraph for precise control; (2) enhancing the capabilities of agents based on CrewAI to complete a variety of tasks. This study aims to delve into the application of LangGraph and CrewAI in multi-agent systems, providing new perspectives for the future development of agent technology, and promoting technological progress and application innovation in the field of large model intelligent agents.

We present Cryoscope--a new 50 deg^2 field-of-view, 1.2 m aperture, K_{dark} survey telescope to be located at Dome C, Antarctica. Cryoscope has an innovative optical-thermal design wherein the entire telescope is cryogenically cooled. Cryoscope also explores new detector technology to cost-effectively tile the full focal plane. Leveraging the dark Antarctic sky and minimizing telescope thermal emission, Cryoscope achieves unprecedented deep, wide, fast and red observations, matching and exceeding volumetric survey speeds from the Ultraviolet Explorer, Vera Rubin Observatory, Nancy Grace Roman Space Telescope, SPHEREx, and NEO Surveyor. By providing coverage beyond wavelengths of 2 mum, we aim to create the most comprehensive dynamic movie of the most obscured reaches of the Universe. Cryoscope will be a dedicated discovery engine for electromagnetic emission from coalescing compact binaries, Earth-like exoplanets orbiting cold stars, and multiple facets of time-domain, stellar and solar system science. In this paper, we describe the scientific drivers and technical innovations for this new discovery engine operating in the K_{dark} passband, why we choose to deploy it in Antarctica, and the status of a fifth-scale prototype designed as a Pathfinder to retire technological risks prior to full-scale implementation. We plan to deploy the Cryoscope Pathfinder to Dome C in December 2026 and the full-scale telescope by 2030.

This paper studies the impact of artificial intelligence on innovation, exploiting the randomized introduction of a new materials discovery technology to 1,018 scientists in the R&D lab of a large U.S. firm. AI-assisted researchers discover 44% more materials, resulting in a 39% increase in patent filings and a 17% rise in downstream product innovation. These compounds possess more novel chemical structures and lead to more radical inventions. However, the technology has strikingly disparate effects across the productivity distribution: while the bottom third of scientists see little benefit, the output of top researchers nearly doubles. Investigating the mechanisms behind these results, I show that AI automates 57% of "idea-generation" tasks, reallocating researchers to the new task of evaluating model-produced candidate materials. Top scientists leverage their domain knowledge to prioritize promising AI suggestions, while others waste significant resources testing false positives. Together, these findings demonstrate the potential of AI-augmented research and highlight the complementarity between algorithms and expertise in the innovative process. Survey evidence reveals that these gains come at a cost, however, as 82% of scientists report reduced satisfaction with their work due to decreased creativity and skill underutilization.

Innovation is a major driver of economic and social development, and information about many kinds of innovation is embedded in semi-structured data from patents and patent applications. Although the impact and novelty of innovations expressed in patent data are difficult to measure through traditional means, ML offers a promising set of techniques for evaluating novelty, summarizing contributions, and embedding semantics. In this paper, we introduce the Harvard USPTO Patent Dataset (HUPD), a large-scale, well-structured, and multi-purpose corpus of English-language patent applications filed to the United States Patent and Trademark Office (USPTO) between 2004 and 2018. With more than 4.5 million patent documents, HUPD is two to three times larger than comparable corpora. Unlike previously proposed patent datasets in NLP, HUPD contains the inventor-submitted versions of patent applications--not the final versions of granted patents--thereby allowing us to study patentability at the time of filing using NLP methods for the first time. It is also novel in its inclusion of rich structured metadata alongside the text of patent filings: By providing each application's metadata along with all of its text fields, the dataset enables researchers to perform new sets of NLP tasks that leverage variation in structured covariates. As a case study on the types of research HUPD makes possible, we introduce a new task to the NLP community--namely, binary classification of patent decisions. We additionally show the structured metadata provided in the dataset enables us to conduct explicit studies of concept shifts for this task. Finally, we demonstrate how HUPD can be used for three additional tasks: multi-class classification of patent subject areas, language modeling, and summarization.

A patent must be deemed novel and non-obvious in order to be granted by the US Patent Office (USPTO). If it is not, a US patent examiner will cite the prior work, or prior art, that invalidates the novelty and issue a non-final rejection. Predicting what claims of the invention should change given the prior art is an essential and crucial step in securing invention rights, yet has not been studied before as a learnable task. In this work we introduce the PatentEdits dataset, which contains 105K examples of successful revisions that overcome objections to novelty. We design algorithms to label edits sentence by sentence, then establish how well these edits can be predicted with large language models (LLMs). We demonstrate that evaluating textual entailment between cited references and draft sentences is especially effective in predicting which inventive claims remained unchanged or are novel in relation to prior art.

Knowledge Graphs (KGs) have been used to support a wide range of applications, from web search to personal assistant. In this paper, we describe three generations of knowledge graphs: entity-based KGs, which have been supporting general search and question answering (e.g., at Google and Bing); text-rich KGs, which have been supporting search and recommendations for products, bio-informatics, etc. (e.g., at Amazon and Alibaba); and the emerging integration of KGs and LLMs, which we call dual neural KGs. We describe the characteristics of each generation of KGs, the crazy ideas behind the scenes in constructing such KGs, and the techniques developed over time to enable industry impact. In addition, we use KGs as examples to demonstrate a recipe to evolve research ideas from innovations to production practice, and then to the next level of innovations, to advance both science and business.

"An idea is nothing more nor less than a new combination of old elements" (Young, J.W.). The widespread adoption of Large Language Models (LLMs) and publicly available ChatGPT have marked a significant turning point in the integration of Artificial Intelligence (AI) into people's everyday lives. This study explores the capability of LLMs in generating novel research ideas based on information from research papers. We conduct a thorough examination of 4 LLMs in five domains (e.g., Chemistry, Computer, Economics, Medical, and Physics). We found that the future research ideas generated by Claude-2 and GPT-4 are more aligned with the author's perspective than GPT-3.5 and Gemini. We also found that Claude-2 generates more diverse future research ideas than GPT-4, GPT-3.5, and Gemini 1.0. We further performed a human evaluation of the novelty, relevancy, and feasibility of the generated future research ideas. This investigation offers insights into the evolving role of LLMs in idea generation, highlighting both its capability and limitations. Our work contributes to the ongoing efforts in evaluating and utilizing language models for generating future research ideas. We make our datasets and codes publicly available.

Recent advancements in artificial intelligence (AI), particularly in large language models (LLMs) such as OpenAI-o1 and DeepSeek-R1, have demonstrated remarkable capabilities in complex domains such as logical reasoning and experimental coding. Motivated by these advancements, numerous studies have explored the application of AI in the innovation process, particularly in the context of scientific research. These AI technologies primarily aim to develop systems that can autonomously conduct research processes across a wide range of scientific disciplines. Despite these significant strides, a comprehensive survey on AI for Research (AI4Research) remains absent, which hampers our understanding and impedes further development in this field. To address this gap, we present a comprehensive survey and offer a unified perspective on AI4Research. Specifically, the main contributions of our work are as follows: (1) Systematic taxonomy: We first introduce a systematic taxonomy to classify five mainstream tasks in AI4Research. (2) New frontiers: Then, we identify key research gaps and highlight promising future directions, focusing on the rigor and scalability of automated experiments, as well as the societal impact. (3) Abundant applications and resources: Finally, we compile a wealth of resources, including relevant multidisciplinary applications, data corpora, and tools. We hope our work will provide the research community with quick access to these resources and stimulate innovative breakthroughs in AI4Research.

Scientific innovation is undergoing a paradigm shift driven by the rapid advancement of Large Language Models (LLMs). As science faces mounting challenges including information overload, disciplinary silos, and diminishing returns on conventional research methods, LLMs are emerging as powerful agents capable not only of enhancing scientific workflows but also of participating in and potentially leading the innovation process. Existing surveys mainly focus on different perspectives, phrases, and tasks in scientific research and discovery, while they have limitations in understanding the transformative potential and role differentiation of LLM. This survey proposes a comprehensive framework to categorize the evolving roles of LLMs in scientific innovation across three hierarchical levels: Evaluator, Collaborator, and Scientist. We distinguish between LLMs' contributions to structured scientific research processes and open-ended scientific discovery, thereby offering a unified taxonomy that clarifies capability boundaries, evaluation criteria, and human-AI interaction patterns at each level. Through an extensive analysis of current methodologies, benchmarks, systems, and evaluation metrics, this survey delivers an in-depth and systematic synthesis on LLM-driven scientific innovation. We present LLMs not only as tools for automating existing processes, but also as catalysts capable of reshaping the epistemological foundations of science itself. This survey offers conceptual clarity, practical guidance, and theoretical foundations for future research, while also highlighting open challenges and ethical considerations in the pursuit of increasingly autonomous AI-driven science. Resources related to this survey can be accessed on GitHub at: https://github.com/haoxuan-unt2024/llm4innovation.

Retrieval-augmented language models often struggle with knowledge-intensive tasks due to inefficient retrieval, unstructured knowledge integration, and single-pass architectures. We present Retrieval-And-Structuring (RAS), a novel framework that dynamically constructs and reasons over query-specific knowledge graphs through iterative retrieval and structuring. RAS introduces four key technical innovations: (1) a themescoped retrieval mechanism that efficiently narrows the search space while maintaining retrieval quality, (2) an action planning module that determines knowledge needs and generates focused sub-queries, (3) a dynamic knowledge structuring approach that converts retrieved text into an evolving knowledge graph, and (4) a graph-augmented answering component that leverages the accumulated structured information. Our framework achieves state-of-the-art performance, surpassing leading baselines by 6.4% with open-source language models and 7.0% with proprietary models on seven knowledge-intensive generation datasets across all evaluation metrics. Detailed ablation studies verify the contribution of each technical component to the overall system performance.

The Patent-Based Idea Generation task asks systems to turn real patents into product ideas viable within three years. We propose MK2, a prompt-centric pipeline: Gemini 2.5 drafts and iteratively edits a prompt, grafting useful fragments from weaker outputs; GPT-4.1 then uses this prompt to create one idea per patent, and an Elo loop judged by Qwen3-8B selects the best prompt-all without extra training data. Across three domains, two evaluator types, and six criteria, MK2 topped the automatic leaderboard and won 25 of 36 tests. Only the materials-chemistry track lagged, indicating the need for deeper domain grounding; yet, the results show that lightweight prompt engineering has already delivered competitive, commercially relevant ideation from patents.

Artificial Intelligence (AI), like any transformative technology, has the potential to be a double-edged sword, leading either toward significant advancements or detrimental outcomes for society as a whole. As is often the case when it comes to widely-used technologies in market economies (e.g., cars and semiconductor chips), commercial interest tends to be the predominant guiding factor. The AI community is at risk of becoming polarized to either take a laissez-faire attitude toward AI development, or to call for government overregulation. Between these two poles we argue for the community of AI practitioners to consciously and proactively work for the common good. This paper offers a blueprint for a new type of innovation infrastructure including 18 concrete milestones to guide AI research in that direction. Our view is that we are still in the early days of practical AI, and focused efforts by practitioners, policymakers, and other stakeholders can still maximize the upsides of AI and minimize its downsides. We talked to luminaries such as recent Nobelist John Jumper on science, President Barack Obama on governance, former UN Ambassador and former National Security Advisor Susan Rice on security, philanthropist Eric Schmidt on several topics, and science fiction novelist Neal Stephenson on entertainment. This ongoing dialogue and collaborative effort has produced a comprehensive, realistic view of what the actual impact of AI could be, from a diverse assembly of thinkers with deep understanding of this technology and these domains. From these exchanges, five recurring guidelines emerged, which form the cornerstone of a framework for beginning to harness AI in service of the public good. They not only guide our efforts in discovery but also shape our approach to deploying this transformative technology responsibly and ethically.

Scientific discovery is a complex cognitive process that has driven human knowledge and technological progress for centuries. While artificial intelligence (AI) has made significant advances in automating aspects of scientific reasoning, simulation, and experimentation, we still lack integrated AI systems capable of performing autonomous long-term scientific research and discovery. This paper examines the current state of AI for scientific discovery, highlighting recent progress in large language models and other AI techniques applied to scientific tasks. We then outline key challenges and promising research directions toward developing more comprehensive AI systems for scientific discovery, including the need for science-focused AI agents, improved benchmarks and evaluation metrics, multimodal scientific representations, and unified frameworks combining reasoning, theorem proving, and data-driven modeling. Addressing these challenges could lead to transformative AI tools to accelerate progress across disciplines towards scientific discovery.

This paper presents Patent-CR, the first dataset created for the patent claim revision task in English. It includes both initial patent applications rejected by patent examiners and the final granted versions. Unlike normal text revision tasks that predominantly focus on enhancing sentence quality, such as grammar correction and coherence improvement, patent claim revision aims at ensuring the claims meet stringent legal criteria. These criteria are beyond novelty and inventiveness, including clarity of scope, technical accuracy, language precision, and legal robustness. We assess various large language models (LLMs) through professional human evaluation, including general LLMs with different sizes and architectures, text revision models, and domain-specific models. Our results indicate that LLMs often bring ineffective edits that deviate from the target revisions. In addition, domain-specific models and the method of fine-tuning show promising results. Notably, GPT-4 outperforms other tested LLMs, but further revisions are still necessary to reach the examination standard. Furthermore, we demonstrate the inconsistency between automated and human evaluation results, suggesting that GPT-4-based automated evaluation has the highest correlation with human judgment. This dataset, along with our preliminary empirical research, offers invaluable insights for further exploration in patent claim revision.

The study of biological materials and bio-inspired materials science is well established; however, surprisingly little knowledge has been systematically translated to engineering solutions. To accelerate discovery and guide insights, an open-source autoregressive transformer large language model (LLM), BioinspiredLLM, is reported. The model was finetuned with a corpus of over a thousand peer-reviewed articles in the field of structural biological and bio-inspired materials and can be prompted to recall information, assist with research tasks, and function as an engine for creativity. The model has proven that it is able to accurately recall information about biological materials and is further enhanced with enhanced reasoning ability, as well as with retrieval-augmented generation to incorporate new data during generation that can also help to traceback sources, update the knowledge base, and connect knowledge domains. BioinspiredLLM also has been shown to develop sound hypotheses regarding biological materials design and remarkably so for materials that have never been explicitly studied before. Lastly, the model showed impressive promise in collaborating with other generative artificial intelligence models in a workflow that can reshape the traditional materials design process. This collaborative generative artificial intelligence method can stimulate and enhance bio-inspired materials design workflows. Biological materials are at a critical intersection of multiple scientific fields and models like BioinspiredLLM help to connect knowledge domains.

The rapid advancement of scientific progress requires innovative tools that can accelerate discovery. While recent AI methods, particularly large language models (LLMs), have shown promise in tasks such as hypothesis generation and experimental design, they fall short in replicating the collaborative nature of real-world scientific practices, where diverse teams of experts work together to tackle complex problems. To address the limitation, we propose an LLM-based multi-agent system, i.e., Virtual Scientists (VirSci), designed to mimic the teamwork inherent in scientific research. VirSci organizes a team of agents to collaboratively generate, evaluate, and refine research ideas. Through comprehensive experiments, we demonstrate that this multi-agent approach outperforms the state-of-the-art method in producing novel and impactful scientific ideas, showing potential in aligning with key insights in the Science of Science field. Our findings suggest that integrating collaborative agents can lead to more innovative scientific outputs, offering a robust system for autonomous scientific discovery.

Scientific idea generation lies at the heart of scientific discovery and has driven human progress-whether by solving unsolved problems or proposing novel hypotheses to explain unknown phenomena. Unlike standard scientific reasoning or general creative generation, idea generation in science is a multi-objective and open-ended task, where the novelty of a contribution is as essential as its empirical soundness. Large language models (LLMs) have recently emerged as promising generators of scientific ideas, capable of producing coherent and factual outputs with surprising intuition and acceptable reasoning, yet their creative capacity remains inconsistent and poorly understood. This survey provides a structured synthesis of methods for LLM-driven scientific ideation, examining how different approaches balance creativity with scientific soundness. We categorize existing methods into five complementary families: External knowledge augmentation, Prompt-based distributional steering, Inference-time scaling, Multi-agent collaboration, and Parameter-level adaptation. To interpret their contributions, we employ two complementary frameworks: Boden's taxonomy of Combinatorial, Exploratory and Transformational creativity to characterize the level of ideas each family expected to generate, and Rhodes' 4Ps framework-Person, Process, Press, and Product-to locate the aspect or source of creativity that each method emphasizes. By aligning methodological advances with creativity frameworks, this survey clarifies the state of the field and outlines key directions toward reliable, systematic, and transformative applications of LLMs in scientific discovery.

In the upcoming decade, deep learning may revolutionize the natural sciences, enhancing our capacity to model and predict natural occurrences. This could herald a new era of scientific exploration, bringing significant advancements across sectors from drug development to renewable energy. To answer this call, we present DeepSpeed4Science initiative (deepspeed4science.ai) which aims to build unique capabilities through AI system technology innovations to help domain experts to unlock today's biggest science mysteries. By leveraging DeepSpeed's current technology pillars (training, inference and compression) as base technology enablers, DeepSpeed4Science will create a new set of AI system technologies tailored for accelerating scientific discoveries by addressing their unique complexity beyond the common technical approaches used for accelerating generic large language models (LLMs). In this paper, we showcase the early progress we made with DeepSpeed4Science in addressing two of the critical system challenges in structural biology research.

We are in the midst of quantum hype with some excessive claims of quantum computing potential, many vendors' and even some research organizations' exaggerations, and a funding frenzy for very low technology readiness level startups. Governments are contributing to this hype with their large quantum initiatives and their technology sovereignty aspirations. Technology hypes are not bad per se since they create emulation, drive innovations and also contribute to attracting new talents. It works as scientists and vendors deliver progress and innovation on a continuous basis after a so-called peak of expectations. It fails with exaggerated overpromises and underdeliveries that last too long. It could cut short research and innovation funding, creating some sort of quantum winter. After looking at the shape and form of technology and science hypes and driving some lessons from past hypes, we investigate the current quantum hype and its specifics. We find that, although there is some significant uncertainty on the potential to create real scalable quantum computers, the scientific and vendor fields are relatively sane and solid compared to other technology hypes. The vendors hype has some profound and disruptive impact on the organization of fundamental research. Also, quantum technologies comprise other fields like quantum telecommunications and quantum sensing with a higher technology readiness level, which are less prone to hype. We then make some proposals to mitigate the potential negative effects of the current quantum hype including recommendations on scientific communication to strengthen the trust in quantum science, vendor behavior improvements, benchmarking methodologies, public education and putting in place a responsible research and innovation approach.

Recent technological advances, especially in the field of machine learning, provide astonishing progress on the road towards artificial general intelligence. However, tasks in current real-world business applications cannot yet be solved by machines alone. We, therefore, identify the need for developing socio-technological ensembles of humans and machines. Such systems possess the ability to accomplish complex goals by combining human and artificial intelligence to collectively achieve superior results and continuously improve by learning from each other. Thus, the need for structured design knowledge for those systems arises. Following a taxonomy development method, this article provides three main contributions: First, we present a structured overview of interdisciplinary research on the role of humans in the machine learning pipeline. Second, we envision hybrid intelligence systems and conceptualize the relevant dimensions for system design for the first time. Finally, we offer useful guidance for system developers during the implementation of such applications.

The exponential growth of knowledge and the increasing complexity of interdisciplinary research pose significant challenges for researchers, including information overload and difficulties in exploring novel ideas. The advancements in large language models (LLMs), such as GPT-4, have shown great potential in enhancing idea proposals, but how to effectively utilize large models for reasonable idea proposal has not been thoroughly explored. This paper proposes a scientific paper idea proposer (SciPIP). Based on a user-provided research background, SciPIP retrieves helpful papers from a literature database while leveraging the capabilities of LLMs to generate more novel and feasible ideas. To this end, 1) we construct a literature retrieval database, extracting lots of papers' multi-dimension information for fast access. Then, a literature retrieval method based on semantics, entity, and citation co-occurrences is proposed to search relevant literature from multiple aspects based on the user-provided background. 2) After literature retrieval, we introduce dual-path idea proposal strategies, where one path infers solutions from the retrieved literature and the other path generates original ideas through model brainstorming. We then combine the two to achieve a good balance between feasibility and originality. Through extensive experiments on the natural language processing (NLP) field, we demonstrate that SciPIP can retrieve citations similar to those of existing top conference papers and generate many ideas consistent with them. Additionally, we evaluate the originality of other ideas generated by SciPIP using large language models, further validating the effectiveness of our proposed method. The code and the database are released at https://github.com/cheerss/SciPIP.

Identifying and predicting the factors that contribute to the success of interdisciplinary research is crucial for advancing scientific discovery. However, there is a lack of methods to quantify the integration of new ideas and technological advancements in astronomical research and how these new technologies drive further scientific breakthroughs. Large language models, with their ability to extract key concepts from vast literature beyond keyword searches, provide a new tool to quantify such processes. In this study, we extracted concepts in astronomical research from 297,807 publications between 1993 and 2024 using large language models, resulting in a set of 24,939 concepts. These concepts were then used to form a knowledge graph, where the link strength between any two concepts was determined by their relevance through the citation-reference relationships. By calculating this relevance across different time periods, we quantified the impact of numerical simulations and machine learning on astronomical research. The knowledge graph demonstrates two phases of development: a phase where the technology was integrated and another where the technology was explored in scientific discovery. The knowledge graph reveals that despite machine learning has made much inroad in astronomy, there is currently a lack of new concept development at the intersection of AI and Astronomy, which may be the current bottleneck preventing machine learning from further transforming the field of astronomy.

Large language models (LLMs) have shown exceptional performance across various text generation tasks but remain under-explored in the patent domain, which offers highly structured and precise language. This paper constructs a dataset to investigate the performance of current LLMs in patent claim generation. Our results demonstrate that generating claims based on patent descriptions outperforms previous research relying on abstracts. Interestingly, current patent-specific LLMs perform much worse than state-of-the-art general LLMs, highlighting the necessity for future research on in-domain LLMs. We also find that LLMs can produce high-quality first independent claims, but their performances markedly decrease for subsequent dependent claims. Moreover, fine-tuning can enhance the completeness of inventions' features, conceptual clarity, and feature linkage. Among the tested LLMs, GPT-4 demonstrates the best performance in comprehensive human evaluations by patent experts, with better feature coverage, conceptual clarity, and technical coherence. Despite these capabilities, comprehensive revision and modification are still necessary to pass rigorous patent scrutiny and ensure legal robustness.